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ACP supports QPP measure 443: "Non-Recommended Cervical Cancer Screening in Adolescent Females” because implementation will likely promote appropriate use of cervical cancer screening in adolescents, the measure is well specified, and specifications include appropriate exclusion criteria for women diagnosed with HIV. Additionally, the measure aligns with United States Preventive Services Task Force (USPSTF) recommendations on cervical cancer screening. While we support this measure, current data on cervical cancer screening in women shows that earlier screening recommendations are not as effective as previously indicated in diagnosing HPV in women aged 16-20 years. The evidence base would benefit from re-evaluation as data surfaces on the benefits and risks of screening in women < 20 years old. In addition, the developers do not cite a performance gap in the measure report, and therefore, we cannot estimate the potential impact of the measure on quality outcomes.